Holding Performance

1%-0% 2%-1% 3%-2% 4%-3% 5%-4% 6%-5%
Top 25 Holdings Portfolio Weight % Shares Owned Shares Change   Sector Mkt Cap (Mil) Total Ret YTD (Daily)  
Amgen Inc 9.86 5,320,127 111,891 healthcare 939.16 10.50
Alexion Pharmaceuticals Inc 6.06 4,398,108 -131,447 healthcare 577.25 -4.52
Celgene Corp 5.51 4,248,968 -71,900 healthcare 524.79 5.62
Regeneron Pharmaceuticals Inc 4.74 1,207,163 73,401 healthcare 450.88 0.83
Biogen Inc 4.13 1,362,604 -39,100 healthcare 393.25 2.40
Vertex Pharmaceuticals Inc 2.70 2,838,888 259,389 healthcare 257.26 58.41
Incyte Corp 2.47 1,767,759 -12,500 healthcare 235.29 22.68
Tesaro Inc 2.41 1,218,715 -174,892 healthcare 229.57 1.14
Seattle Genetics Inc 2.10 3,040,282 -227,439 healthcare 199.59 23.82
Biomarin Pharmaceutical Inc 1.94 1,963,034 -12,600 healthcare 184.39 6.80
ACADIA Pharmaceuticals Inc 1.91 4,780,980 0 healthcare 182.20 11.69
Ultragenyx Pharmaceutical Inc 1.71 1,913,978 0 healthcare 162.84 -13.85
Neurocrine Biosciences Inc 1.58 3,412,022 -64,829 healthcare 150.67 33.80
Alkermes PLC 1.50 2,521,111 0 healthcare 142.44 1.78
Intercept Pharmaceuticals Inc 1.49 1,112,768 0 healthcare 141.98 -0.70
Radius Health Inc 1.41 3,184,330 -468,485 healthcare 134.19 1.97
Ionis Pharmaceuticals Inc 1.34 2,570,377 0 healthcare 127.93 -7.46
Exelixis Inc 1.30 5,750,140 -633,100 healthcare 123.80 40.71
GW Pharmaceuticals PLC ADR 1.22 928,561 -115,913 healthcare 115.87 2.69
Sage Therapeutics Inc 1.07 1,506,493 1,000 healthcare 101.54 42.62
Acceleron Pharma Inc 1.03 3,669,602 0 healthcare 98.05 9.80
Portola Pharmaceuticals Inc 0.99 2,704,725 0 healthcare 93.80 70.23
Alnylam Pharmaceuticals Inc 0.98 1,811,378 0 healthcare 93.54 32.24
Spark Therapeutics Inc 0.97 1,446,320 0 healthcare 92.25 5.21
The Medicines Co 0.94 1,707,508 -356,500 healthcare 89.51 52.71
YTD Return through 04-24-17| Portfolio Holdings as of 02-28-17